货号

RABZ031

别名Alternative Name

COL1A1;Collagen alpha-1(I) chain (Alpha-1 type I collagen); Collagen I/COL1A1; Type I collagen is a member of group I collagen (fibrillar forming collagen)

应用

WB, ICC/IF, IP

反应种属

Human, Mouse, Rat

稀释比

WB-1:1000-1:2000; IF: 1:50; IP-1:20-1:50

SwissProt ID

P02452

宿主

Rabbit

偶联物

Unconjugated

修饰

Unmodified

基因 ID

1277

基因名

COL1A1

亚型

IgG

克隆性

Monoclonal Antibody

克隆号

R02-5E5

研究领域

Signal Transduction

分子量

Calculated MW: 139 kDa; Observed MW: 139 kDa

免疫原

Recombinant protein of human Collagen I

背景信息

This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet- derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

纯化方式

Affinity Purified

形式

Liquid

存储缓冲液

1xPBS(pH 7.4), 150mM NaCl, 50% Glycerol, 0.02% Sodium azide and 0.05% BSA

保存温度

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

纯化方式

Affinity Purified

形式

Liquid

存储缓冲液

1xPBS(pH 7.4), 150mM NaCl, 50% Glycerol, 0.02% Sodium azide and 0.05% BSA

保存温度

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

WB

1:1000-1:2000

IF

1:50

IP

1:20-1:50