货号

RABZ028

别名Alternative Name

SLC7A11; CCBR1; Cysteine/glutamate transporter; solute carrier family 7

应用

WB, ICC/IF, IP

反应种属

Human, Mouse, Rat

稀释比

WB-1:1000-1:4000; IF-1:50-1:200; IP-1:50

SwissProt ID

Q9UPY5

宿主

Rabbit

偶联物

Unconjugated

修饰

Unmodified

基因 ID

23657

基因名

SLC7A11

亚型

IgG

克隆性

Monoclonal Antibody

克隆号

R08-2C5

分子量

Calculated MW: 55 kDa; Observed MW: 55 kDa

免疫原

A synthetic peptide of human xCT

研究领域

Signal Transduction

背景信息

This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator  of  Kaposi  sarcoma-associated  herpesvirus  fusion  and  entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

纯化方式

Affinity Purified

形式

Liquid

存储缓冲液

1xPBS(pH 7.4), 150mM NaCl, 50% Glycerol, 0.02% Sodium azide and 0.05% BSA

保存温度

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

纯化方式

Affinity Purified

形式

Liquid

存储缓冲液

1xPBS(pH 7.4), 150mM NaCl, 50% Glycerol, 0.02% Sodium azide and 0.05% BSA

保存温度

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

WB

1:1000-1:4000

IF

1:50-1:200

IP

1:50