肿瘤的发生发展与细胞凋亡异常、细胞周期失调以及受体酪氨酸激酶(RTK)的异常激活密切相关。研究这些分类有助于揭示肿瘤的发病机制,并为开发抗癌药物提供靶点。
Apoptosis(凋亡):凋亡过程异常与肿瘤的发生发展密切相关,研究细胞凋亡机制有助于寻找肿瘤治疗靶点。
Cell Cycle / Checkpoint Control(细胞周期 / 检查点控制):肿瘤细胞通常存在细胞周期调控异常,通过研究细胞周期及其检查点控制,可以开发抗癌药物。
RTK(受体酪氨酸激酶):受体酪氨酸激酶异常激活常导致细胞过度增殖,与肿瘤发生相关,是重要的抗癌药物研发靶点。
以下是徕曼相关产品部分清单:
徕曼货号 |
徕曼产品名 |
种属 |
应用 |
靶点 |
产品分类 |
研究领域 |
RAB012 |
ALIX Recombinant Rabbit MAB(PT0109R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
Alix |
Apoptosis |
肿瘤 |
RAB018 |
Aurora A Recombinant Rabbit MAB(PT0150R) |
Human |
WB, IHC, IF, IP, ELISA |
Aurora A |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB029 |
FGFR1 Recombinant Rabbit MAB(PT0207R) |
Human |
WB, IHC, IF, IP, ELISA |
FGF Receptor 1 |
RTK |
肿瘤 |
RAB033 |
CDK6 Recombinant Rabbit MAB(PT0069R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
Cdk6 |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB044 |
Rad21 Recombinant Rabbit MAB(PT0134R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
Rad21 |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB049 |
Cyclin E1 Recombinant Rabbit MAB(PT0164R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
Cyclin E1 |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB066 |
Ki67 Recombinant Rabbit MAB(PT0321R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
Ki-67 |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB080 |
c-Myc Recombinant Rabbit MAB(PT0228R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
c-Myc |
Apoptosis |
肿瘤 |
RAB086 |
p21 Recombinant Rabbit MAB(PT0237R) |
Human,Rat |
WB, IHC, IF, IP, ELISA |
P21 |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB087 |
Cyclin D1 Recombinant Rabbit MAB(PT0238R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
Cyclin D1 |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB094 |
LC3B Recombinant Rabbit MAB(PT0235R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
LC3B |
Apoptosis |
肿瘤 |
RAB095 |
FAK Recombinant Rabbit MAB(PT0245R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
FAK |
RTK |
肿瘤 |
RAB099 |
Lamin B1 Recombinant Rabbit MAB(PT0286R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
Lamin B1 |
Apoptosis |
肿瘤 |
RAB105 |
Caspase-9 Recombinant Rabbit MAB(PT0299R) |
Human,Mouse |
WB, IF, ELISA |
Caspase-9 |
Apoptosis |
肿瘤 |
RAB113 |
LC3A Recombinant Rabbit MAB(PT0130R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
LC3A |
Apoptosis |
肿瘤 |
RAB117 |
Bcl-XL Recombinant Rabbit MAB(PT0244R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
Bcl-x |
Apoptosis |
肿瘤 |
RAB121 |
Bax Recombinant Rabbit MAB(PT0301R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
Bax |
Apoptosis |
肿瘤 |
RAB131 |
p27 KIP 1 Recombinant Rabbit MAB(PT0324R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
p27 |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB133 |
Cyclin B1 (Phospho Ser126) Recombinant Rabbit MAB(PT0070R) |
Human |
WB, IHC, IF, IP, ELISA |
Cyclin B1 |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB140 |
Bad Recombinant Rabbit MAB(PT0219R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
Bad |
Apoptosis |
肿瘤 |
RAB141 |
PCNA Recombinant Rabbit MAB(PT0224R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
PCNA |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB143 |
Survivin Recombinant Rabbit MAB(PT0343R) |
Human,Mouse,Rat |
WB, IF, IP, ELISA |
Survivin |
Apoptosis |
肿瘤 |
RAB148 |
Rad51 Recombinant Rabbit MAB(PT0083R) |
Human,Mouse,Rat |
WB, IF, IP, ELISA |
RAD51 |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB165 |
p16 INK4A Recombinant Rabbit MAB(PT0242R) |
Human,Mouse,Rat |
WB, IF, IP, ELISA |
p16 |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB166 |
Aurora B Recombinant Rabbit MAB(PT0246R) |
Human |
WB, IHC, IF, IP, ELISA |
ARK-2 |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB199 |
Chk2 Recombinant Rabbit MAB(PT0474R) |
Human,Mouse |
WB, IHC, IF, IP, ELISA |
Chk2 |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB207 |
Cytochrome C Recombinant Rabbit MAB(PT0394R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
Cytochrome C |
Apoptosis |
肿瘤 |
RAB215 |
Cdc2 Recombinant Rabbit MAB(PT0406R) |
Human,Mouse |
WB,IHC,IF,IP,ELISA |
CDK1/CDC2 |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB217 |
RRM1 Recombinant Rabbit MAB(PT0842R) |
Human,Mouse,Rat |
WB, IF, IP, ELISA |
RRM1 |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB225 |
PP2A α/β Recombinant Rabbit MAB(PT0537R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
PP2A alpha + beta |
Cell Cycle / Checkpoint Control |
肿瘤 |
RAB261 |
Bcl-2 Recombinant Rabbit MAB(PT0487R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
Bcl-2 |
Apoptosis |
肿瘤 |
RAB284 |
EGFR Recombinant Rabbit MAB(PT0520R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
EGFR |
RTK |
肿瘤 |
RAB297 |
Chk2 Recombinant Rabbit MAB(PT0672R) |
Human,Mouse,Rat |
WB, IHC, IF, IP, ELISA |
Chk2 |
Cell Cycle / Checkpoint Control |
肿瘤 |