Key Features
|
货号 |
RABZ025 |
|
别名Alternative Name |
PRKAA2; AMPK; AMPK2; 5'-AMP-activated protein kinase catalytic subunit alpha- 2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase |
|
应用 |
WB, IP |
|
反应种属 |
Human, Mouse, Rat |
|
稀释比 |
WB-1:500-1:1000; IP-1:20-1:50 |
|
SwissProt ID |
P54646 |
|
宿主 |
Rabbit |
|
偶联物 |
Unconjugated |
|
修饰 |
Unmodified |
|
基因 ID |
5563 |
|
基因名 |
PRKAA2 |
|
亚型 |
IgG |
|
克隆性 |
Monoclonal Antibody |
|
克隆号 |
R06-9C7 |
|
分子量 |
Calculated MW: 62 kDa; Observed MW: 62 kDa |
|
免疫原 |
Recombinant protein of human AMPK alpha 2 |
|
研究领域 |
Neuroscience |
|
背景信息 |
AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits, each of which is encoded by two or three distinct genes (α1, 2; β1, 2; γ1, 2, 3). The kinase is activated by an elevated AMP/ATP ratio due to cellular and environmental stress, such as heat shock, hypoxia, and ischemia. |
|
纯化方式 |
Affinity Purified |
|
形式 |
Liquid |
|
存储缓冲液 |
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
|
保存温度 |
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
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