HSP90AB1 ;

HSP90B ;

HSPC2 ;

HSPCB ;

Heat shock protein HSP 90-beta ;

HSP 90 ;

Heat shock 84 kDa ;

HSP 84 ;

HSP84

Gene name

HSP90AB1

Protein Name

Heat shock protein HSP 90-beta

Organism

Gene ID

UniProt ID

Human

3326

P08238

Mouse

15516

P11499

Rat

301252

P34058

Cellular Localization

Cytoplasm, Nuclear

Tissue specificity

Amygdala,Brain cortex,Colon,Colon carcinoma,Embryon

Function

Function:Molecular chaperone. Has ATPase activity.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the heat shock protein 90 family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Homodimer. Interacts with TP53/p53 (By similarity). Interacts with UNC45A. Binding to UNC45A involves 2 UNC45A monomers per HSP90AB1 dimer.

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-20°C

IHC:

1:200-1000

WB:

1:500-5000

IF:

1:200-1000

ELISA

1:5000-20000

IP:

1:50-200