Cleaved-Caspase 8 Mouse mAb

Key Features

货号	MABZ009
别名Alternative Name	CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH
应用	WB, IHC-F, IHC-P, ICC/IF
反应种属	Human, Mouse, Rat
稀释比	WB-1:500-1:1000; IHC-1:50-1:100; IF-1:50-1:200
SwissProt ID	Q14790
宿主	Mouse
偶联物	Unconjugated
修饰	Unmodified
基因 ID	841
基因名	CASP8
亚型	IgG1
克隆性	Monoclonal Antibody
克隆号	4C2-3G4-5G7
分子量	Calculated MW: 55 kDa; Observed MW: 18，43,57 kDa
免疫原	Recombinant Protein of Caspase-8
研究领域	Cell Biology
背景信息	This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit.
纯化方式	Affinity Purified
形式	Liquid
存储缓冲液	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
保存温度	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

图片

Western blot analysis of Caspase 8 in K562, 3T3, MCF-7 and Jurkat lysates using Caspase 8 antibody.

Western blot analysis of Caspase 8 in THP-1, rat Brain, Hela lysates using Caspase 8 antibody.

Western blot analysis of Caspase 8 in Jurkat, MOLT4 lysates using Caspase 8 antibody.

Immunocytochemistry analysis of Caspase 8 (green) in Hela using Caspase 8 antibody,and DAPI(blue).

性能

纯化方式	Affinity Purified
形式	Liquid
存储缓冲液	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
保存温度	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.