Gene name

HSPA1A

Alternative Names

HSP72; HSPA1; HSP70I; HSPA1B; HSP70-1; HSP70-1A.

UniProt ID

P0DMV8

Background

In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

组成

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化工艺

Protein A

储存

-20°C

WB:

1:500-1000

IF:

1:50-200